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ALPS Medical Breakthroughs ETF

SBIO

ALPS Funds

ALPS Medical Breakthroughs ETF (SBIO) on the Akinda fund screen (AAOIFI-derived): Not halal. Coverage 100.00%. Below: the fund under all five rulebooks, its facts and every holding with its own verdict.

Akinda fund screen

Akinda fund screen (AAOIFI-derived)Not halalCoverage: 100.00%
  • Halal 11.79%
  • Doubtful 0.00%
  • Not halal 88.23%
  • Not rated 0.00%

The bar is scaled to fit; the figures are as reported, and the buckets do not always total 100%.

Coverage is the share of the fund's weight we hold a usable verdict for. Below 95%, a fund is rated only when the weight we can see already breaches the 5% limit; otherwise it is not rated by this method.

Fund facts

Issuer
ALPS Funds
Venue (where it trades)
United States
Domicile (where it is registered)
United States
Reporting currency
USD
Expense ratio
0.50%
AUM
178.64M USD
Holdings
100 (100 screened)
Basket as of (provider)
27 Oct 2026
Basket fetched by Akinda
27 Oct 2026
Verdict updated
3 Nov 2026

Venue is where a fund trades; domicile is where it is registered. London-listed funds are domiciled in Ireland or Luxembourg, so use Venue for UK ETFs.

Five rulebooks

RulebookVerdictHalalNot halalSplit (0–100%)
Akinda fund screen (AAOIFI)Not halal11.79%88.23%
DJIMNot halal13.42%84.24%
FTSENot halal4.03%95.99%
MSCINot halal4.03%95.99%
S&PNot halal15.58%81.65%

Every bar uses the same 0–100% scale. Index rulebooks report only halal and not-halal weight; uncoloured weight is weight that rulebook does not classify. Coverage is published for the Akinda fund screen only.

The fund screen and the four index rulebooks answer different questions, so they are expected to disagree. A fund can be doubtful on our fund screen and halal under S&P; both are correct.

Holdings

1–50 of 100 holdings, largest first · basket as of 27 Oct 2026
No.HoldingWeightAkinda (AAOIFI)DJIMFTSEMSCIS&P
1
ORKAOruka Therapeutics Inc.
4.07%Not halalNot halalNot halalNot halalNot halal
2
MANEVeraDermics Inc.
3.91%Not halalNot halalNot halalNot halalNot halal
3
CGONCG oncology Inc.
3.71%Not halalNot halalNot halalNot halalNot halal
4
DFTXDefinium Therapeutics Inc.
3.26%Not halalNot halalNot halalNot halalNot halal
5
TVTXTravere Therapeutics Inc.
3.20%HalalHalalNot halalNot halalHalal
6
DNTHDianthus Therapeutics Inc.
3.02%Not halalNot halalNot halalNot halalNot halal
7
EWTXEdgewise Therapeutics Inc.
2.89%Not halalNot halalNot halalNot halalNot halal
8
RLAYRelay Therapeutics Inc.
2.70%Not halalNot halalNot halalNot halalNot halal
9
XENEXenon Pharmaceuticals Inc.
2.36%Not halalNot ratedNot halalNot halalNot rated
10
ACADACADIA Pharmaceuticals Inc.
2.31%HalalHalalNot halalNot halalHalal
11
AMLXAmylyx Pharmaceuticals Inc.
2.31%Not halalNot halalNot halalNot halalNot halal
12
IDYAIdeaya Biosciences Inc.
2.16%Not halalNot halalNot halalNot halalNot halal
13
TARSTarsus Pharmaceuticals Inc.
2.09%HalalHalalNot halalNot halalHalal
14
DNLIDenali Therapeutics Inc.
2.03%Not halalNot halalNot halalNot halalNot halal
15
IRONDisc Medicine Inc.
2.03%Not halalNot halalNot halalNot halalNot halal
16
DYNDyne Therapeutics Inc.
2.00%Not halalNot halalNot halalNot halalNot halal
17
ZLABZai Lab Ltd.
1.86%Not halalNot halalNot halalNot halalNot halal
18
VRDNViridian Therapeutics Inc.
1.80%Not halalNot halalNot halalNot halalNot halal
19
MBXMBX Biosciences Inc.
1.65%Not halalNot halalNot halalNot halalNot halal
20
NAMSNewamsterdam Pharma Co. NV
1.59%Not halalNot halalNot halalNot halalNot halal
21
CLDXCelldex Therapeutics Inc.
1.58%Not halalNot halalNot halalNot halalNot halal
22
SLSSELLAS Life Sciences Group Inc.
1.56%Not halalNot halalNot halalNot halalNot halal
23
VCELVericel Corp.
1.50%HalalHalalHalalHalalHalal
24
AGIOAgios Pharmaceuticals Inc.
1.50%Not halalNot halalNot halalNot halalNot halal
25
XNCRXencor Inc.
1.48%Not halalNot halalNot halalNot halalNot halal
26
LKFTLakefront Biotherapeutics NV
1.44%Not halalNot halalNot halalNot halalHalal
27
VERAVera Therapeutics Inc.
1.39%Not halalNot halalNot halalNot halalNot halal
28
IMNMImmunome Inc.
1.38%Not halalNot halalNot halalNot halalNot halal
29
BCRXBioCryst Pharmaceuticals Inc.
1.37%HalalHalalNot halalNot halalHalal
30
SRPTSarepta Therapeutics Inc.
1.29%Not halalHalalHalalHalalHalal
31
PVLAPalvella Therapeutics Inc.
1.24%Not halalNot halalNot halalNot halalNot halal
32
MLYSMineralys Therapeutics Inc.
1.24%Not halalNot halalNot halalNot halalNot halal
33
ZBIOZenas Biopharma Inc.
1.21%Not halalNot halalNot halalNot halalNot halal
34
MAZEMaze Therapeutics Inc.
1.17%Not halalNot halalNot halalNot halalNot halal
35
KLRAKailera Therapeutics Inc.
1.13%Not halalNot halalNot halalNot halalNot halal
36
STOKStoke Therapeutics Inc.
1.12%Not halalNot halalNot halalNot halalNot halal
37
IMCRImmunocore Holdings PLC
1.10%Not halalNot halalNot halalNot halalNot halal
38
GENBGenerate Biomedicines Inc.
1.08%Not halalNot halalNot halalNot halalNot halal
39
NUVBNuvation Bio Inc.
1.08%Not halalNot halalNot halalNot halalNot halal
40
CMPSCompass Pathways PLC
1.04%Not halalNot halalNot halalNot halalNot halal
41
GPCRStructure Therapeutics Inc.
1.02%Not halalNot halalNot halalNot halalNot halal
42
TSHATaysha Gene Therapies Inc.
0.89%Not halalNot halalNot halalNot halalNot halal
43
NKTRNektar Therapeutics
0.87%Not halalNot halalNot halalNot halalNot halal
44
LBRXLB Pharmaceuticals Inc.
0.86%Not halalNot halalNot halalNot halalNot halal
45
TYRATyra Biosciences Inc.
0.83%Not halalNot halalNot halalNot halalNot halal
46
RAPPRapport Therapeutics Inc.
0.83%Not halalNot halalNot halalNot halalNot halal
47
BCAXBicara Therapeutics Inc.
0.76%Not halalNot halalNot halalNot halalNot halal
48
SPTXSeaport Therapeutics Inc.
0.76%Not halalNot halalNot halalNot halalNot halal
49
VORVor BioPharma Inc.
0.74%Not halalNot halalNot halalNot halalNot halal
50
IMTXImmatics NV
0.73%Not halalNot halalNot halalNot halalNot halal

Not rated means we hold no usable verdict for that company; it is never treated as compliant.

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