No. | Holding | Weight | Akinda (AAOIFI) | DJIM | FTSE | MSCI | S&P |
|---|
| 1 | | 5.15% | Halal | Halal | Not halal | Not halal | Halal |
| 2 | KYMRKYMERA THERAPEUTICS INC COMMON STOCK USD.0001 | 4.35% | Not halal | Not rated | Not halal | Not halal | Not rated |
| 3 | KODKODIAK SCIENCES INC COMMON STOCK USD.0001 | 2.65% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 4 | UTHRUNITED THERAPEUTICS CORP COMMON STOCK USD.01 | 2.52% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 5 | NTRANATERA INC COMMON STOCK | 2.48% | Halal | Halal | Not halal | Not halal | Halal |
| 6 | VRTXVERTEX PHARMACEUTICALS INC COMMON STOCK USD.01 | 2.34% | Halal | Halal | Halal | Halal | Halal |
| 7 | RVMDREVOLUTION MEDICINES INC COMMON STOCK | 2.23% | Not halal | Not rated | Not halal | Not halal | Not rated |
| 8 | INSMINSMED INC COMMON STOCK USD.01 | 2.22% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 9 | PCVXVAXCYTE INC COMMON STOCK USD.001 | 2.10% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 10 | MRNAMODERNA INC COMMON STOCK USD.0001 | 2.06% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 11 | BBIOBRIDGEBIO PHARMA INC COMMON STOCK | 1.97% | Not halal | Not rated | Not halal | Not halal | Not rated |
| 12 | SYRESPYRE THERAPEUTICS INC COMMON STOCK USD.0001 | 1.96% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 13 | ALNYALNYLAM PHARMACEUTICALS INC COMMON STOCK USD.01 | 1.91% | Halal | Halal | Not halal | Not halal | Halal |
| 14 | PRAXPRAXIS PRECISION MEDICINES I COMMON STOCK USD.0001 | 1.84% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 15 | DNTHDIANTHUS THERAPEUTICS INC COMMON STOCK USD.001 | 1.81% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 16 | RYTMRHYTHM PHARMACEUTICALS INC COMMON STOCK | 1.79% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 17 | ALKSALKERMES PLC COMMON STOCK USD.01 | 1.77% | Halal | Halal | Not halal | Not halal | Halal |
| 18 | CYTKCYTOKINETICS INC COMMON STOCK USD.001 | 1.77% | Not halal | Not rated | Not halal | Not halal | Not rated |
| 19 | MIRMMIRUM PHARMACEUTICALS INC COMMON STOCK | 1.68% | Halal | Halal | Not halal | Not halal | Halal |
| 20 | TNGXTANGO THERAPEUTICS INC COMMON STOCK USD.0001 | 1.61% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 21 | ARWRARROWHEAD PHARMACEUTICALS IN COMMON STOCK USD.001 | 1.58% | Halal | Halal | Not halal | Not halal | Halal |
| 22 | CGONCG ONCOLOGY INC COMMON STOCK | 1.58% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 23 | ERASERASCA INC COMMON STOCK USD.0001 | 1.56% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 24 | RLAYRELAY THERAPEUTICS INC COMMON STOCK USD.001 | 1.55% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 25 | MDGLMADRIGAL PHARMACEUTICALS INC COMMON STOCK USD.0001 | 1.52% | Halal | Halal | Not halal | Not halal | Halal |
| 26 | SRRKSCHOLAR ROCK HOLDING CORP COMMON STOCK USD.001 | 1.48% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 27 | TVTXTRAVERE THERAPEUTICS INC COMMON STOCK USD.0001 | 1.43% | Halal | Halal | Not halal | Not halal | Halal |
| 28 | IRONDISC MEDICINE INC COMMON STOCK USD.0001 | 1.36% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 29 | TWSTTWIST BIOSCIENCE CORP COMMON STOCK USD.00001 | 1.35% | Halal | Halal | Not halal | Not halal | Halal |
| 30 | DYNDYNE THERAPEUTICS INC COMMON STOCK USD.0001 | 1.27% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 31 | BIIBBIOGEN INC COMMON STOCK USD.0005 | 1.21% | Halal | Halal | Halal | Halal | Halal |
| 32 | GRALGRAIL INC COMMON STOCK | 1.21% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 33 | VRDNVIRIDIAN THERAPEUTICS INC COMMON STOCK USD.01 | 1.20% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 34 | NRIXNURIX THERAPEUTICS INC COMMON STOCK | 1.14% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 35 | BEAMBEAM THERAPEUTICS INC COMMON STOCK USD.01 | 1.08% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 36 | CLDXCELLDEX THERAPEUTICS INC COMMON STOCK USD.001 | 1.06% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 37 | DNLIDENALI THERAPEUTICS INC COMMON STOCK USD.01 | 1.05% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 38 | KRYSKRYSTAL BIOTECH INC COMMON STOCK USD.00001 | 1.04% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 39 | HALOHALOZYME THERAPEUTICS INC COMMON STOCK USD.001 | 1.03% | Not halal | Halal | Not halal | Not halal | Halal |
| 40 | PTGXPROTAGONIST THERAPEUTICS INC COMMON STOCK USD.00001 | 1.00% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 41 | ROIVROIVANT SCIENCES LTD COMMON STOCK USD.0000001 | 1.00% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 42 | AMGNAMGEN INC COMMON STOCK USD.0001 | 0.99% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 43 | GILD.TOGILEAD SCIENCES INC COMMON STOCK USD.001 | 0.94% | Not rated | Not rated | Not rated | Not rated | Not rated |
| 44 | COGTCOGENT BIOSCIENCES INC COMMON STOCK USD.001 | 0.93% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 45 | IDYAIDEAYA BIOSCIENCES INC COMMON STOCK USD.0001 | 0.93% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 46 | VERAVERA THERAPEUTICS INC COMMON STOCK USD.001 | 0.93% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 47 | IMVTIMMUNOVANT INC COMMON STOCK USD.0001 | 0.92% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 48 | XNCRXENCOR INC COMMON STOCK USD.01 | 0.89% | Not halal | Not halal | Not halal | Not halal | Not halal |
| 49 | VCYTVERACYTE INC COMMON STOCK USD.001 | 0.88% | Halal | Halal | Halal | Halal | Halal |
| 50 | IONSIONIS PHARMACEUTICALS INC COMMON STOCK USD.001 | 0.88% | Not halal | Not halal | Not halal | Not halal | Not halal |
